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Antibodies against Alpha-Synuclein Reduce Oligomerization in Living Cells
Recent research implicates soluble aggregated forms of α-synuclein as neurotoxic species with a central role in the pathogenesis of Parkinson's disease and related disorders. The pathway by which α-synuclein aggregates is believed to follow a step-wise pattern, in which dimers and smaller oligo...
Autores principales: | Näsström, Thomas, Gonçalves, Susana, Sahlin, Charlotte, Nordström, Eva, Screpanti Sundquist, Valentina, Lannfelt, Lars, Bergström, Joakim, Outeiro, Tiago F., Ingelsson, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205056/ https://www.ncbi.nlm.nih.gov/pubmed/22073131 http://dx.doi.org/10.1371/journal.pone.0027230 |
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