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Molecular network topology and reliability for multipurpose diagnosis
This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205134/ https://www.ncbi.nlm.nih.gov/pubmed/22072875 http://dx.doi.org/10.2147/IJN.S24935 |
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author | Jalil, MA Moongfangklang, N Innate, K Mitatha, S Ali, J Yupapin, PP |
author_facet | Jalil, MA Moongfangklang, N Innate, K Mitatha, S Ali, J Yupapin, PP |
author_sort | Jalil, MA |
collection | PubMed |
description | This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of the trapping molecules by light in the network is described and the theoretical background is reviewed. The quality of the network is analyzed and calculated in terms of signal transmission (ie, signal to noise ratio and crosstalk effects). Results obtained show that a bus network has advantages over star and ring networks, where the use of mesh networks is possible. In application, a thin film network can be fabricated in the form of a waveguide and embedded in artificial bone, which can be connected to the required drug targets. The particular drug/nutrient can be transported to the required targets via the particular network used. |
format | Online Article Text |
id | pubmed-3205134 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-32051342011-11-09 Molecular network topology and reliability for multipurpose diagnosis Jalil, MA Moongfangklang, N Innate, K Mitatha, S Ali, J Yupapin, PP Int J Nanomedicine Original Research This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of the trapping molecules by light in the network is described and the theoretical background is reviewed. The quality of the network is analyzed and calculated in terms of signal transmission (ie, signal to noise ratio and crosstalk effects). Results obtained show that a bus network has advantages over star and ring networks, where the use of mesh networks is possible. In application, a thin film network can be fabricated in the form of a waveguide and embedded in artificial bone, which can be connected to the required drug targets. The particular drug/nutrient can be transported to the required targets via the particular network used. Dove Medical Press 2011 2011-10-19 /pmc/articles/PMC3205134/ /pubmed/22072875 http://dx.doi.org/10.2147/IJN.S24935 Text en © 2011 Jalil et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Jalil, MA Moongfangklang, N Innate, K Mitatha, S Ali, J Yupapin, PP Molecular network topology and reliability for multipurpose diagnosis |
title | Molecular network topology and reliability for multipurpose diagnosis |
title_full | Molecular network topology and reliability for multipurpose diagnosis |
title_fullStr | Molecular network topology and reliability for multipurpose diagnosis |
title_full_unstemmed | Molecular network topology and reliability for multipurpose diagnosis |
title_short | Molecular network topology and reliability for multipurpose diagnosis |
title_sort | molecular network topology and reliability for multipurpose diagnosis |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205134/ https://www.ncbi.nlm.nih.gov/pubmed/22072875 http://dx.doi.org/10.2147/IJN.S24935 |
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