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Physicochemical properties and biocompatibility of a polymer-paclitaxel conjugate for cancer treatment

BACKGROUND: Poly(L-γ-glutamylglutamine) paclitaxel (PGG-PTX) conjugate is a non-diblock polymeric drug nanoparticle intended to improve the therapeutic index of paclitaxel. The purpose of the present study was to elucidate further the physicochemical properties of PGG-PTX in order to proceed with it...

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Detalles Bibliográficos
Autores principales:	Yang, Danbo, Van, Sang, Liu, Jian, Wang, Jing, Jiang, Xinguo, Wang, Yiting, Yu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205149/ https://www.ncbi.nlm.nih.gov/pubmed/22072890 http://dx.doi.org/10.2147/IJN.S25044

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