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Ocular melanoma: Keep your eyes open for late brain metastases

BACKGROUND: The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. CASE DESCRIPTION: The authors report a case of a 28-year-old woman presenting with a single b...

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Detalles Bibliográficos
Autores principales: de A. Silva, Danilo O., Matis, Georgios K., Costa, Leonardo F., Kitamura, Matheus A. P., de C. Júnior, Eduardo V., Barbosa, Breno J. A. P., Santiago, Isaac B., Silva, Tatiane I., de P. A. Silva, Fabiana Q., Pereira, Carlos U., Azevedo Filho, Hildo R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205508/
https://www.ncbi.nlm.nih.gov/pubmed/22059139
http://dx.doi.org/10.4103/2152-7806.85985
Descripción
Sumario:BACKGROUND: The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. CASE DESCRIPTION: The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. CONCLUSION: The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.