Ocular melanoma: Keep your eyes open for late brain metastases

BACKGROUND: The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. CASE DESCRIPTION: The authors report a case of a 28-year-old woman presenting with a single b...

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Autores principales: de A. Silva, Danilo O., Matis, Georgios K., Costa, Leonardo F., Kitamura, Matheus A. P., de C. Júnior, Eduardo V., Barbosa, Breno J. A. P., Santiago, Isaac B., Silva, Tatiane I., de P. A. Silva, Fabiana Q., Pereira, Carlos U., Azevedo Filho, Hildo R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205508/
https://www.ncbi.nlm.nih.gov/pubmed/22059139
http://dx.doi.org/10.4103/2152-7806.85985
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author de A. Silva, Danilo O.
Matis, Georgios K.
Costa, Leonardo F.
Kitamura, Matheus A. P.
de C. Júnior, Eduardo V.
Barbosa, Breno J. A. P.
Santiago, Isaac B.
Silva, Tatiane I.
de P. A. Silva, Fabiana Q.
Pereira, Carlos U.
Azevedo Filho, Hildo R. C.
author_facet de A. Silva, Danilo O.
Matis, Georgios K.
Costa, Leonardo F.
Kitamura, Matheus A. P.
de C. Júnior, Eduardo V.
Barbosa, Breno J. A. P.
Santiago, Isaac B.
Silva, Tatiane I.
de P. A. Silva, Fabiana Q.
Pereira, Carlos U.
Azevedo Filho, Hildo R. C.
author_sort de A. Silva, Danilo O.
collection PubMed
description BACKGROUND: The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. CASE DESCRIPTION: The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. CONCLUSION: The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.
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spelling pubmed-32055082011-11-06 Ocular melanoma: Keep your eyes open for late brain metastases de A. Silva, Danilo O. Matis, Georgios K. Costa, Leonardo F. Kitamura, Matheus A. P. de C. Júnior, Eduardo V. Barbosa, Breno J. A. P. Santiago, Isaac B. Silva, Tatiane I. de P. A. Silva, Fabiana Q. Pereira, Carlos U. Azevedo Filho, Hildo R. C. Surg Neurol Int Case Report BACKGROUND: The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. CASE DESCRIPTION: The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. CONCLUSION: The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed. Medknow Publications Pvt Ltd 2011-10-12 /pmc/articles/PMC3205508/ /pubmed/22059139 http://dx.doi.org/10.4103/2152-7806.85985 Text en Copyright: © 2011 de A. Silva DO. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
de A. Silva, Danilo O.
Matis, Georgios K.
Costa, Leonardo F.
Kitamura, Matheus A. P.
de C. Júnior, Eduardo V.
Barbosa, Breno J. A. P.
Santiago, Isaac B.
Silva, Tatiane I.
de P. A. Silva, Fabiana Q.
Pereira, Carlos U.
Azevedo Filho, Hildo R. C.
Ocular melanoma: Keep your eyes open for late brain metastases
title Ocular melanoma: Keep your eyes open for late brain metastases
title_full Ocular melanoma: Keep your eyes open for late brain metastases
title_fullStr Ocular melanoma: Keep your eyes open for late brain metastases
title_full_unstemmed Ocular melanoma: Keep your eyes open for late brain metastases
title_short Ocular melanoma: Keep your eyes open for late brain metastases
title_sort ocular melanoma: keep your eyes open for late brain metastases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205508/
https://www.ncbi.nlm.nih.gov/pubmed/22059139
http://dx.doi.org/10.4103/2152-7806.85985
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