Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides

1-Carbamoyl-2-oxopropyl acetate derivatives were synthesized through an acetoxylation process to methylene with the aid of (diacetoxyiodo)benzene (DIB) as the oxidant. Not only mild reaction conditions, but also excellent yields and good substrate scope make the present protocol potentially useful i...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wei-Bing, Chen, Cui, Zhang, Qing, Zhu, Zhi-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205772/
https://www.ncbi.nlm.nih.gov/pubmed/22049301
http://dx.doi.org/10.3762/bjoc.7.167
_version_ 1782215361774485504
author Liu, Wei-Bing
Chen, Cui
Zhang, Qing
Zhu, Zhi-Bo
author_facet Liu, Wei-Bing
Chen, Cui
Zhang, Qing
Zhu, Zhi-Bo
author_sort Liu, Wei-Bing
collection PubMed
description 1-Carbamoyl-2-oxopropyl acetate derivatives were synthesized through an acetoxylation process to methylene with the aid of (diacetoxyiodo)benzene (DIB) as the oxidant. Not only mild reaction conditions, but also excellent yields and good substrate scope make the present protocol potentially useful in organic synthesis.
format Online
Article
Text
id pubmed-3205772
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-32057722011-11-02 Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides Liu, Wei-Bing Chen, Cui Zhang, Qing Zhu, Zhi-Bo Beilstein J Org Chem Letter 1-Carbamoyl-2-oxopropyl acetate derivatives were synthesized through an acetoxylation process to methylene with the aid of (diacetoxyiodo)benzene (DIB) as the oxidant. Not only mild reaction conditions, but also excellent yields and good substrate scope make the present protocol potentially useful in organic synthesis. Beilstein-Institut 2011-10-19 /pmc/articles/PMC3205772/ /pubmed/22049301 http://dx.doi.org/10.3762/bjoc.7.167 Text en Copyright © 2011, Liu et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Liu, Wei-Bing
Chen, Cui
Zhang, Qing
Zhu, Zhi-Bo
Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title_full Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title_fullStr Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title_full_unstemmed Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title_short Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides
title_sort hypervalent iodine(iii)-induced methylene acetoxylation of 3-oxo-n-substituted butanamides
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205772/
https://www.ncbi.nlm.nih.gov/pubmed/22049301
http://dx.doi.org/10.3762/bjoc.7.167
work_keys_str_mv AT liuweibing hypervalentiodineiiiinducedmethyleneacetoxylationof3oxonsubstitutedbutanamides
AT chencui hypervalentiodineiiiinducedmethyleneacetoxylationof3oxonsubstitutedbutanamides
AT zhangqing hypervalentiodineiiiinducedmethyleneacetoxylationof3oxonsubstitutedbutanamides
AT zhuzhibo hypervalentiodineiiiinducedmethyleneacetoxylationof3oxonsubstitutedbutanamides

Ejemplares similares