l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry

Opioid peptides are involved in various pathophysiological processes, including algesia, epilepsy, and drug dependence. A strong association between l-DOPA-induced dyskinesia (LID) and elevated prodynorphin mRNA levels has been established in both patients and in animal models of Parkinson's di...

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Detalles Bibliográficos
Autores principales: Hanrieder, Jörg, Ljungdahl, Anna, Fälth, Maria, Mammo, Sofie Eriksson, Bergquist, Jonas, Andersson, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205869/
https://www.ncbi.nlm.nih.gov/pubmed/21737418
http://dx.doi.org/10.1074/mcp.M111.009308

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