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High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations

All immunoglobulin G molecules carry N-glycans, which modulate their biological activity. Changes in N-glycosylation of IgG associate with various diseases and affect the activity of therapeutic antibodies and intravenous immunoglobulins. We have developed a novel 96-well protein G monolithic plate...

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Detalles Bibliográficos
Autores principales: Pučić, Maja, Knežević, Ana, Vidič, Jana, Adamczyk, Barbara, Novokmet, Mislav, Polašek, Ozren, Gornik, Olga, Šupraha-Goreta, Sandra, Wormald, Mark R., Redžić, Irma, Campbell, Harry, Wright, Alan, Hastie, Nicholas D., Wilson, James F., Rudan, Igor, Wuhrer, Manfred, Rudd, Pauline M., Josić, Djuro, Lauc, Gordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205872/
https://www.ncbi.nlm.nih.gov/pubmed/21653738
http://dx.doi.org/10.1074/mcp.M111.010090