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Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization
Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation. In addition, recent studies suggest that isoflurane may directly promote the for...
Autores principales: | Zhang, Yiying, Zhen, Yu, Dong, Yuanlin, Xu, Zhipeng, Yue, Yun, Golde, Todd E., Tanzi, Rudolph E., Moir, Robert D., Xie, Zhongcong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206055/ https://www.ncbi.nlm.nih.gov/pubmed/22069482 http://dx.doi.org/10.1371/journal.pone.0027019 |
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