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Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization

Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation. In addition, recent studies suggest that isoflurane may directly promote the for...

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Detalles Bibliográficos
Autores principales: Zhang, Yiying, Zhen, Yu, Dong, Yuanlin, Xu, Zhipeng, Yue, Yun, Golde, Todd E., Tanzi, Rudolph E., Moir, Robert D., Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206055/
https://www.ncbi.nlm.nih.gov/pubmed/22069482
http://dx.doi.org/10.1371/journal.pone.0027019

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