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Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis
In acute lymphoblastic leukemia (ALL) patients, the bone marrow niche is widely known to be an important element of treatment response and relapse. Furthermore, a characteristic liver pathology observed in ALL patients implies that the hepatic microenvironment provides an extramedullary niche for le...
Autores principales: | Kato, Itaru, Niwa, Akira, Heike, Toshio, Fujino, Hisanori, Saito, Megumu K., Umeda, Katsutsugu, Hiramatsu, Hidefumi, Ito, Mamoru, Morita, Makiko, Nishinaka, Yoko, Adachi, Souichi, Ishikawa, Fumihiko, Nakahata, Tatsutoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206061/ https://www.ncbi.nlm.nih.gov/pubmed/22069486 http://dx.doi.org/10.1371/journal.pone.0027042 |
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