Cargando…

Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia

BACKGROUND: Apolipoprotein E (apoE) is a major protein of the lipoprotein transport system that plays important roles in lipid homeostasis and protection from atherosclerosis. ApoE is characterized by structural plasticity and thermodynamic instability and can undergo significant structural rearrang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Georgiadou, Dimitra, Chroni, Angeliki, Vezeridis, Alexander, Zannis, Vassilis I., Stratikos, Efstratios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206067/ https://www.ncbi.nlm.nih.gov/pubmed/22069485 http://dx.doi.org/10.1371/journal.pone.0027037

Ejemplares similares

The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific
por: Dafnis, Ioannis, et al.
Publicado: (2016)

Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux
por: Daniil, Georgios, et al.
Publicado: (2013)

Modern prevalence of dysbetalipoproteinemia (Fredrickson-Levy-Lees type III hyperlipoproteinemia)
por: Pallazola, Vincent A., et al.
Publicado: (2019)

Therapeutic management of hyperlipoproteinemia (a)
por: Kosmas, Constantine E, et al.
Publicado: (2019)

Role of apolipoproteins, ABCA1 and LCAT in the biogenesis of normal and aberrant high density lipoproteins
por: Zannis, Vassilis I., et al.
Publicado: (2017)

Loss-of-Function Homozygous Variant in LPL Causes Type I Hyperlipoproteinemia and Renal Lipidosis
por: Wu, Hongyan, et al.
Publicado: (2023)

Eruptive Xanthomas Caused by Primary Type V Hyperlipoproteinemia
por: Nakamura, Yoshihiro, et al.
Publicado: (2021)

Hyperlipoproteinemia(a) and Severe Coronary Artery Lesion Types
por: Ilina, Larisa N., et al.
Publicado: (2022)

Cross interactions between Apolipoprotein E and amyloid proteins in neurodegenerative diseases
por: Loch, Rolf Antonie, et al.
Publicado: (2023)

The Internal Sequence of the Peptide-Substrate Determines Its N-Terminus Trimming by ERAP1
por: Evnouchidou, Irini, et al.
Publicado: (2008)

Novel Pharmacological Therapies for the Management of Hyperlipoproteinemia(a)
por: Kosmas, Constantine E., et al.
Publicado: (2023)

A Case of Type V Hyperlipoproteinemia Resistant to Insulin Treatment
por: Mangeshkar, Shaunak, et al.
Publicado: (2023)

Case of familial hyperlipoproteinemia type III hypertriglyceridemia induced acute pancreatitis: Role for outpatient apheresis maintenance therapy
por: Saleh, Mohannad Abou, et al.
Publicado: (2017)

SUN-056 Recurrent Pancreatitis Induced by Uncontrolled Type V Hyperlipoproteinemia
por: Rivera Rivero, Bianshly, et al.
Publicado: (2019)

Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia
por: Wang, Shuping, et al.
Publicado: (2022)

Primary and secondary prevention of cardiovascular disease in patients with hyperlipoproteinemia (a)
por: Grützmacher, P., et al.
Publicado: (2017)

A rare case of COVID-19 pneumonia with severe hyperlipoproteinemia
por: Shimoda, Masafumi, et al.
Publicado: (2022)

Hyperlipoproteinemia (a) is associated with breast cancer in a Han Chinese population
por: Xu, Jing, et al.
Publicado: (2020)

Management of Patients with Type V Hyperlipoproteinemia: An Uncommon Phenotype of Dyslipidemia with Chylomicronemia and Severe Hypertriglyceridemia
por: Chang, Ya-Hui, et al.
Publicado: (2022)

A Case of Hypothyroidism and Type 2 Diabetes Associated with Type V Hyperlipoproteinemia and Eruptive Xanthomas
por: Park, Jeong Rang, et al.
Publicado: (2005)

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
por: Hegele, Robert A., et al.
Publicado: (2009)

Influence of metabolic syndrome superposition on familial combined hyperlipoproteinemia cardiovascular complication rate
por: Cicero, Arrigo F.G., et al.
Publicado: (2013)

Case report of one month and 15 days old baby with type V hyperlipoproteinemia (HLP)
por: Dildar, Shabnam, et al.
Publicado: (2020)

Increased cardiovascular risk associated with hyperlipoproteinemia (a) and the challenges of current and future therapeutic possibilities
por: Fras, Zlatko
Publicado: (2020)

Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages
por: Nissilä, Eija, et al.
Publicado: (2018)

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism
por: Maben, Zachary, et al.
Publicado: (2021)

Recurrent Acute Pancreatitis in a Patient with Type IIb hyperlipoproteinemia: A Case Report and Review of the Literature in Korea
por: Kim, Byung Kook, et al.
Publicado: (2006)

Author Correction: Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism
por: Maben, Zachary, et al.
Publicado: (2023)

The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases
por: Papakyriakou, Athanasios, et al.
Publicado: (2017)

The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy
por: Mpakali, Anastasia, et al.
Publicado: (2021)

Apolipoprotein E in VLDL and LDL With Apolipoprotein C‐III is Associated With a Lower Risk of Coronary Heart Disease
por: Mendivil, Carlos O., et al.
Publicado: (2013)

Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation
por: Papakyriakou, Athanasios, et al.
Publicado: (2022)

Clinical benefit of long-term lipoprotein apheresis in patients with severe hypercholesterolemia or Lp(a)-hyperlipoproteinemia with progressive cardiovascular disease
por: Heigl, Franz, et al.
Publicado: (2015)

Lipoprotein(a)-hyperlipoproteinemia as cause of chronic spinal cord ischemia resulting in progressive myelopathy – successful treatment with lipoprotein apheresis
por: Heigl, Franz, et al.
Publicado: (2017)

Assessing the impact of pain-linked Nav1.7 variants: An example of two variants with no biophysical effect
por: Le Cann, Kim, et al.
Publicado: (2021)

Variations in high density cholesterol levels based on apolipoprotein E variant and exercise type
por: Chang, Huan-Cheng, et al.
Publicado: (2023)

Apolipoprotein C-III is linked to the insulin resistance and beta-cell dysfunction that are present in rheumatoid arthritis
por: Martín-González, Candelaria, et al.
Publicado: (2022)

Association between cognitive impairment and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia
por: Rao, Wenwang, et al.
Publicado: (2021)

Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia
por: Rao, Wenwang, et al.
Publicado: (2021)

Apolipoprotein E Gene Variants on the Risk of End Stage Renal Disease
por: Xue, Cheng, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o4mlhn9ctl8g95j3bhr6he9rf9