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Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings

OBJECTIVES: Cataracts are the most common cause of blindness worldwide, with cataract surgery being the most common ophthalmic procedure. To our best knowledge, this is the first case-control study with a large number of participants to evaluate ocular blood flow in patients with cataracts. MATERIAL...

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Autores principales: Mohammadi, Afshin, Khorasani, Nilofar, Moloudi, Farzad, Ghasemi-rad, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206125/
https://www.ncbi.nlm.nih.gov/pubmed/22069356
http://dx.doi.org/10.2147/OPTH.S25759
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author Mohammadi, Afshin
Khorasani, Nilofar
Moloudi, Farzad
Ghasemi-rad, Mohammad
author_facet Mohammadi, Afshin
Khorasani, Nilofar
Moloudi, Farzad
Ghasemi-rad, Mohammad
author_sort Mohammadi, Afshin
collection PubMed
description OBJECTIVES: Cataracts are the most common cause of blindness worldwide, with cataract surgery being the most common ophthalmic procedure. To our best knowledge, this is the first case-control study with a large number of participants to evaluate ocular blood flow in patients with cataracts. MATERIALS AND METHODS: Color Doppler and duplex sonography of the orbital vessels was performed in 224 eyes of 112 patients with known bilateral age-related cataracts and in 76 eyes of 38 healthy age- and sex-matched volunteers. RESULTS: The mean ± (standard deviation [SD]) of peak systolic velocity (PSV) of the ophthalmic artery in patients with cataracts (34.59 ± 22.49 cm/second) was significantly different to that in controls (52.11 ± 14.01 cm/second) (P < 0.001). The mean ± SD PSV of the central retinal artery in patients with cataracts (15.31 ± 4.93 cm/second) was significantly different to that in controls (9.61 ± 5.64 cm/second) (P < 0.001). CONCLUSION: The mean PSV and resistive index (RI) of the ophthalmic and central retinal arteries were lower in cataract patients when compared with normal subjects. This suggests that ocular hypoperfusion and changes in ocular hemodynamic may have a role in the formation of age-related cataracts.
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spelling pubmed-32061252011-11-08 Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings Mohammadi, Afshin Khorasani, Nilofar Moloudi, Farzad Ghasemi-rad, Mohammad Clin Ophthalmol Original Research OBJECTIVES: Cataracts are the most common cause of blindness worldwide, with cataract surgery being the most common ophthalmic procedure. To our best knowledge, this is the first case-control study with a large number of participants to evaluate ocular blood flow in patients with cataracts. MATERIALS AND METHODS: Color Doppler and duplex sonography of the orbital vessels was performed in 224 eyes of 112 patients with known bilateral age-related cataracts and in 76 eyes of 38 healthy age- and sex-matched volunteers. RESULTS: The mean ± (standard deviation [SD]) of peak systolic velocity (PSV) of the ophthalmic artery in patients with cataracts (34.59 ± 22.49 cm/second) was significantly different to that in controls (52.11 ± 14.01 cm/second) (P < 0.001). The mean ± SD PSV of the central retinal artery in patients with cataracts (15.31 ± 4.93 cm/second) was significantly different to that in controls (9.61 ± 5.64 cm/second) (P < 0.001). CONCLUSION: The mean PSV and resistive index (RI) of the ophthalmic and central retinal arteries were lower in cataract patients when compared with normal subjects. This suggests that ocular hypoperfusion and changes in ocular hemodynamic may have a role in the formation of age-related cataracts. Dove Medical Press 2011 2011-10-18 /pmc/articles/PMC3206125/ /pubmed/22069356 http://dx.doi.org/10.2147/OPTH.S25759 Text en © 2011 Mohammadi et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Mohammadi, Afshin
Khorasani, Nilofar
Moloudi, Farzad
Ghasemi-rad, Mohammad
Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title_full Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title_fullStr Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title_full_unstemmed Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title_short Evaluation of retrobulbar blood flow in patients with age-related cataract; color Doppler ultrasonographic findings
title_sort evaluation of retrobulbar blood flow in patients with age-related cataract; color doppler ultrasonographic findings
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206125/
https://www.ncbi.nlm.nih.gov/pubmed/22069356
http://dx.doi.org/10.2147/OPTH.S25759
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