Immunoglobulin E in health and disease

The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. Apart from allergic disea...

Descripción completa

Detalles Bibliográficos
Autor principal: Amarasekera, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2011
Materias:
Current Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206235/
https://www.ncbi.nlm.nih.gov/pubmed/22053291
http://dx.doi.org/10.5415/apallergy.2011.1.1.12
Descripción
Sumario:The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. Apart from allergic diseases, IgE is involved in pathogenesis of other disorders. Much controversy exists about the control of total IgE (tIgE) levels and allergen-specific IgE (sIgE) profiles in allergic individuals. This review aims at giving a comprehensive overview of IgE molecule and discussing the issues related to its importance in clinical setting.

Ejemplares similares