Immunoglobulin E in health and disease

The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. Apart from allergic disea...

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Detalles Bibliográficos
Autor principal: Amarasekera, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2011
Materias:
Current Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206235/
https://www.ncbi.nlm.nih.gov/pubmed/22053291
http://dx.doi.org/10.5415/apallergy.2011.1.1.12
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author Amarasekera, M.
author_facet Amarasekera, M.
author_sort Amarasekera, M.
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description The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. Apart from allergic diseases, IgE is involved in pathogenesis of other disorders. Much controversy exists about the control of total IgE (tIgE) levels and allergen-specific IgE (sIgE) profiles in allergic individuals. This review aims at giving a comprehensive overview of IgE molecule and discussing the issues related to its importance in clinical setting.
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spelling pubmed-32062352011-11-03 Immunoglobulin E in health and disease Amarasekera, M. Asia Pac Allergy Current Review The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. Apart from allergic diseases, IgE is involved in pathogenesis of other disorders. Much controversy exists about the control of total IgE (tIgE) levels and allergen-specific IgE (sIgE) profiles in allergic individuals. This review aims at giving a comprehensive overview of IgE molecule and discussing the issues related to its importance in clinical setting. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2011-04 2011-04-19 /pmc/articles/PMC3206235/ /pubmed/22053291 http://dx.doi.org/10.5415/apallergy.2011.1.1.12 Text en Copyright © 2011. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Current Review
Amarasekera, M.
Immunoglobulin E in health and disease
title Immunoglobulin E in health and disease
title_full Immunoglobulin E in health and disease
title_fullStr Immunoglobulin E in health and disease
title_full_unstemmed Immunoglobulin E in health and disease
title_short Immunoglobulin E in health and disease
title_sort immunoglobulin e in health and disease
topic Current Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206235/
https://www.ncbi.nlm.nih.gov/pubmed/22053291
http://dx.doi.org/10.5415/apallergy.2011.1.1.12
work_keys_str_mv AT amarasekeram immunoglobulineinhealthanddisease

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