Basal Activation of Type I Interferons (Alpha2 and Beta) and 2′5′OAS Genes: Insights into Differential Expression Profiles of Interferon System Components in Systemic Sclerosis

Objective. Systemic sclerosis (SSc) is a complex autoimmune disease in which interferons (IFNs) may play an essential role. We hypothesized that type I and III IFNs may be found in increased levels in patients and be responsible for SSc autoimmune status. Methods. Type I and III IFN and ISG basal ex...

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Detalles Bibliográficos
Autores principales: de Oliveira, Danilo Bretas, Almeida, Gabriel Magno de Freitas, Guedes, Antônio Carlos Martins, Santos, Flávia Patrícia Sena Teixeira, Bonjardim, Claudio Antônio, Ferreira, Paulo César Peregrino, Kroon, Erna Geessien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206376/
https://www.ncbi.nlm.nih.gov/pubmed/22121373
http://dx.doi.org/10.1155/2011/275617

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