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Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial

BACKGROUND: In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated inflammatory response (IR). METHODS: We performed a randomi...

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Detalles Bibliográficos
Autores principales:	Jiménez, Juan J, Iribarren, José L, Brouard, Maitane, Hernández, Domingo, Palmero, Salomé, Jiménez, Alejandro, Lorente, Leonardo, Machado, Patricia, Borreguero, Juan M, Raya, José M, Martín, Beatriz, Pérez, Rosalía, Martínez, Rafael, Mora, María L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206427/ https://www.ncbi.nlm.nih.gov/pubmed/21999189 http://dx.doi.org/10.1186/1749-8090-6-138

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