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Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

We recently reported that expression levels of tumor necrosis factor (TNF) receptors, TNFR1 and TNFR2, are significantly changed in the brains and cerebrospinal fluid (CSF) with Alzheimer's disease (AD). Moreover, we also found that, in an Alzheimer's mouse model, genetic deletion of TNF r...

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Detalles Bibliográficos
Autores principales: Jiang, Hong, Hampel, Harald, Prvulovic, David, Wallin, Anders, Blennow, Kaj, Li, Rena, Shen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206445/
https://www.ncbi.nlm.nih.gov/pubmed/21978728
http://dx.doi.org/10.1186/1750-1326-6-69