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The role of haploinsufficiency of RPS14 and p53 activation in the molecular pathogenesis of the 5q- syndrome
In recent years we have gained great insight into the molecular pathogenesis of the 5q- syndrome, a distinct subtype of myelodysplasia. The demonstration of haploinsufficiency of the ribosomal gene RPS14 (mapping to the commonly deleted region) and the finding that this is the cause of the erythroid...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PAGEPress Publications
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206529/ https://www.ncbi.nlm.nih.gov/pubmed/22053272 http://dx.doi.org/10.4081/pr.2011.s2.e10 |