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Pathobiology of ALK-negative anaplastic large cell lymphoma

The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotyp...

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Autores principales: Pileri, Stefano A., Agostinelli, Claudio, Bacci, Francesco, Sabattini, Elena, Sagramoso, Carlo, Falini, Brunangelo, Piccaluga, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206530/
https://www.ncbi.nlm.nih.gov/pubmed/22053281
http://dx.doi.org/10.4081/pr.2011.s2.e5
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author Pileri, Stefano A.
Agostinelli, Claudio
Bacci, Francesco
Sabattini, Elena
Sagramoso, Carlo
Falini, Brunangelo
Piccaluga, Pier Paolo
author_facet Pileri, Stefano A.
Agostinelli, Claudio
Bacci, Francesco
Sabattini, Elena
Sagramoso, Carlo
Falini, Brunangelo
Piccaluga, Pier Paolo
author_sort Pileri, Stefano A.
collection PubMed
description The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented.
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spelling pubmed-32065302011-11-03 Pathobiology of ALK-negative anaplastic large cell lymphoma Pileri, Stefano A. Agostinelli, Claudio Bacci, Francesco Sabattini, Elena Sagramoso, Carlo Falini, Brunangelo Piccaluga, Pier Paolo Pediatr Rep Article The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented. PAGEPress Publications 2011-06-22 /pmc/articles/PMC3206530/ /pubmed/22053281 http://dx.doi.org/10.4081/pr.2011.s2.e5 Text en ©Copyright S.A. Pileri et al., 2011 This work is licensed under a Creative Commons Attribution NonCommercial 3.0 License (CC BYNC 3.0). Licensee PAGEPress, Italy
spellingShingle Article
Pileri, Stefano A.
Agostinelli, Claudio
Bacci, Francesco
Sabattini, Elena
Sagramoso, Carlo
Falini, Brunangelo
Piccaluga, Pier Paolo
Pathobiology of ALK-negative anaplastic large cell lymphoma
title Pathobiology of ALK-negative anaplastic large cell lymphoma
title_full Pathobiology of ALK-negative anaplastic large cell lymphoma
title_fullStr Pathobiology of ALK-negative anaplastic large cell lymphoma
title_full_unstemmed Pathobiology of ALK-negative anaplastic large cell lymphoma
title_short Pathobiology of ALK-negative anaplastic large cell lymphoma
title_sort pathobiology of alk-negative anaplastic large cell lymphoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206530/
https://www.ncbi.nlm.nih.gov/pubmed/22053281
http://dx.doi.org/10.4081/pr.2011.s2.e5
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