Cargando…

The Drosophila Ral Gtpase Regulates Developmental Cell Shape Changes through the Jun Nh(2)-Terminal Kinase Pathway

The Ral GTPase is activated by RalGDS, which is one of the effector proteins for Ras. Previous studies have suggested that Ral might function to regulate the cytoskeleton; however, its in vivo function is unknown. We have identified a Drosophila homologue of Ral that is widely expressed during embry...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sawamoto, Kazunobu, Winge, Per, Koyama, Shinya, Hirota, Yuki, Yamada, Chiharu, Miyao, Sachiyo, Yoshikawa, Shingo, Jin, Ming-hao, Kikuchi, Akira, Okano, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206575/ https://www.ncbi.nlm.nih.gov/pubmed/10427090

Ejemplares similares

Antitumor Effects of Ral-GTPases Downregulation in Glioblastoma
por: Cemeli, Tània, et al.
Publicado: (2022)

Ral GTPase–activating protein regulates the malignancy of pancreatic ductal adenocarcinoma
por: Yoshimachi, Shingo, et al.
Publicado: (2021)

Regulation of c-Jun NH(2)-Terminal Kinase for Islet Transplantation
por: Noguchi, Hirofumi
Publicado: (2019)

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases
por: Hurd, Catherine A., et al.
Publicado: (2020)

Krox-20 inhibits Jun-NH(2)-terminal kinase/c-Jun to control Schwann cell proliferation and death
por: Parkinson, David B., et al.
Publicado: (2004)

TD-60 links RalA GTPase function to the CPC in mitosis
por: Papini, Diana, et al.
Publicado: (2015)

Characterisation of the Ral GTPase inhibitor RBC8 in human and mouse platelets
por: Walsh, Tony G., et al.
Publicado: (2019)

RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases
por: O. Santos, Adriana, et al.
Publicado: (2016)

Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production
por: Cao, Mingxin, et al.
Publicado: (2023)

Ral GTPases regulate neurite branching through GAP-43 and the exocyst complex
por: Lalli, Giovanna, et al.
Publicado: (2005)

RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis
por: Nászai, Máté, et al.
Publicado: (2021)

Activation of the c-Jun NH(2)-terminal kinase pathway by coronavirus infectious bronchitis virus promotes apoptosis independently of c-Jun
por: Fung, To Sing, et al.
Publicado: (2017)

Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation
por: Iida, Tomoya, et al.
Publicado: (2019)

The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells
por: Ljubicic, Sanda, et al.
Publicado: (2009)

Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system
por: Ommer, Andrea, et al.
Publicado: (2019)

RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS
por: Seibold, Marcel, et al.
Publicado: (2019)

Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes
por: Ghoroghi, Shima, et al.
Publicado: (2021)

Ral GTPase is essential for actin dynamics and Golgi apparatus distribution in mouse oocyte maturation
por: Sun, Ming-Hong, et al.
Publicado: (2021)

Regulation of c-Jun NH(2)-terminal Kinase ( Jnk) Gene Expression during T Cell Activation
por: Weiss, Linda, et al.
Publicado: (2000)

Specific effects of c-Jun NH2-terminal kinase-interacting protein 1 in neuronal axons
por: Tang, Shu, et al.
Publicado: (2016)

Role of the MAPK/cJun NH(2)-terminal kinase signaling pathway in starvation-induced autophagy
por: Barutcu, Seda Avcioglu, et al.
Publicado: (2018)

RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes
por: Johansson, Joel, et al.
Publicado: (2019)

Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles
por: Norden, Pieter R., et al.
Publicado: (2020)

Inhibition of c-Jun NH(2)-terminal kinase or extracellular signal-regulated kinase improves lung injury
por: Lee, Hui Su, et al.
Publicado: (2004)

Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH(2)-Terminal Kinase Activation
por: Wu, Yicun, et al.
Publicado: (2014)

The activation of c-Jun NH(2)-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
por: Jia, Guang, et al.
Publicado: (2014)

c-Jun NH2-terminal kinase suppression significantly inhibits the growth of transplanted breast tumors in mice
por: Huang, You-Cheng, et al.
Publicado: (2020)

NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy
por: Luo, Haixia, et al.
Publicado: (2020)

Regulated Membrane Localization of Tiam1, Mediated by the NH(2)-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH(2)-terminal Kinase Activation
por: Michiels, Frits, et al.
Publicado: (1997)

RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation
por: Galino, Jorge, et al.
Publicado: (2019)

RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer
por: Wang, Pengpeng, et al.
Publicado: (2020)

CTA at RAL
por: Patargias, George
Publicado: (2022)

Lack of Correlation between Activation of Jun–NH(2)-terminal Kinase and Induction of Apoptosis after Detachment of Epithelial Cells
por: Khwaja, Asim, et al.
Publicado: (1997)

Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways
Publicado: (1996)

Matrix Survival Signaling: From Fibronectin via Focal Adhesion Kinase to C-Jun Nh(2)-Terminal Kinase
por: Almeida, Eduardo A.C., et al.
Publicado: (2000)

PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH(2)-terminal kinase activation
por: Yanase, Noriko, et al.
Publicado: (2012)

G12 Signaling through c-Jun NH(2)-Terminal Kinase Promotes Breast Cancer Cell Invasion
por: Juneja, Juhi, et al.
Publicado: (2011)

C-Jun NH(2)-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle
por: Ok, Seong-Ho, et al.
Publicado: (2011)

The cJUN NH(2)-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation
por: Girnius, Nomeda, et al.
Publicado: (2018)

The cJUN NH(2)-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution
por: Girnius, Nomeda, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ujhe6vges5ehngud041848hmeh