Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran: HBV seroprevalence in hemodialysis patients

BACKGROUND: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units. OBJECTIVES: To determine the prevalence of anti-HBs antibody in hemodialysis patients and the correlation between levels of anti-HBs antibody with other factors. PATIENTS AND METHODS: HBsAg, anti-HBs and a...

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Detalles Bibliográficos
Autores principales: Mostaghni, Amir Ahmad, Soltanian, Alireza, Mokhtari, Elaheh, Japoni, Sara, Mehrabani, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206679/
https://www.ncbi.nlm.nih.gov/pubmed/22087144
Descripción
Sumario:BACKGROUND: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units. OBJECTIVES: To determine the prevalence of anti-HBs antibody in hemodialysis patients and the correlation between levels of anti-HBs antibody with other factors. PATIENTS AND METHODS: HBsAg, anti-HBs and anti-HBc antibodies level in 119 hemodialysis patients were evaluated by enzyme-linked immunosorbent assay. RESULTS: Seroconversion (anti-HBs antibody >10 IU/L) was found in 22 patients. Minimum protective antibody level was found in patients aged ≥60 years. Statistically significant correlation was not found between anti-HBs antibody and gender. Ten (8.4%) patients had abnormal ALT and/or AST. Prevalence of HBsAg, anti-HBc antibody, HBeAg and anti-HBe antibody were found in 8 (6.72%), 24 (25.16%), 2 (1.68%) and 3 (2.52%) patients, respectively. CONCLUSIONS: Periodic assessment of anti-HBs antibody level is strongly recommended in patients undergoing hemodialysis.

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