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Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

Previous experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP. Here we use a genome-scale model of human cell metabolism to inves...

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Detalles Bibliográficos
Autores principales: Vazquez, Alexei, Markert, Elke K., Oltvai, Zoltán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206798/
https://www.ncbi.nlm.nih.gov/pubmed/22073143
http://dx.doi.org/10.1371/journal.pone.0025881

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