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DPO multiplex PCR as an alternative to culture and susceptibility testing to detect Helicobacter pylori and its resistance to clarithromycin
BACKGROUND: Macrolide resistance in Helicobacter pylori is the major risk factor for treatment failure when using a proton pump inhibitor-clarithromycin containing therapy. Macrolide resistance is due to a few mutations on the 23S ribomosal subunit encoded by the 23S rRNA gene. The present study aim...
Autores principales: | Lehours, Philippe, Siffré, Elodie, Mégraud , Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206832/ https://www.ncbi.nlm.nih.gov/pubmed/22004003 http://dx.doi.org/10.1186/1471-230X-11-112 |
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