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MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R
To study the roles of microRNA-223 (miR-223) in regulation of cell growth, we established a miR-223 over-expression model in HeLa cells infected with miR-223 by Lentivirus pLL3.7 system. We observed in this model that miR-223 significantly suppressed the proliferation, growth rate, colony formation...
Autores principales: | Jia, Cheng You, Li, Hui Hui, Zhu, Xu Chao, Dong, Yi Wei, Fu, Da, Zhao, Qian Lei, Wu, Wei, Wu, Xing Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206888/ https://www.ncbi.nlm.nih.gov/pubmed/22073238 http://dx.doi.org/10.1371/journal.pone.0027008 |
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