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MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R

To study the roles of microRNA-223 (miR-223) in regulation of cell growth, we established a miR-223 over-expression model in HeLa cells infected with miR-223 by Lentivirus pLL3.7 system. We observed in this model that miR-223 significantly suppressed the proliferation, growth rate, colony formation...

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Detalles Bibliográficos
Autores principales: Jia, Cheng You, Li, Hui Hui, Zhu, Xu Chao, Dong, Yi Wei, Fu, Da, Zhao, Qian Lei, Wu, Wei, Wu, Xing Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206888/
https://www.ncbi.nlm.nih.gov/pubmed/22073238
http://dx.doi.org/10.1371/journal.pone.0027008

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