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Profiling of Substrate Specificities of 3C-Like Proteases from Group 1, 2a, 2b, and 3 Coronaviruses

BACKGROUND: Coronaviruses (CoVs) can be classified into alphacoronavirus (group 1), betacoronavirus (group 2), and gammacoronavirus (group 3) based on diversity of the protein sequences. Their 3C-like protease (3CL(pro)), which catalyzes the proteolytic processing of the polyproteins for viral repli...

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Detalles Bibliográficos
Autores principales:	Chuck, Chi-Pang, Chow, Hak-Fun, Wan, David Chi-Cheong, Wong, Kam-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206940/ https://www.ncbi.nlm.nih.gov/pubmed/22073294 http://dx.doi.org/10.1371/journal.pone.0027228

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