RpkA, a Highly Conserved GPCR with a Lipid Kinase Domain, Has a Role in Phagocytosis and Anti-Bacterial Defense

RpkA (Receptor phosphatidylinositol kinase A) is an unusual seven-helix transmembrane protein of Dictyostelium discoideum with a G protein coupled receptor (GPCR) signature and a C-terminal lipid kinase domain (GPCR-PIPK) predicted as a phosphatidylinositol-4-phosphate 5-kinase. RpkA-homologs are pr...

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Detalles Bibliográficos
Autores principales: Riyahi, Tanja Y., Frese, Frederike, Steinert, Michael, Omosigho, Napoleon N., Glöckner, Gernot, Eichinger, Ludwig, Orabi, Benoit, Williams, Robin S. B., Noegel, Angelika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206951/
https://www.ncbi.nlm.nih.gov/pubmed/22073313
http://dx.doi.org/10.1371/journal.pone.0027311

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