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Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation

Engineered model substrates are powerful tools for examining interactions between stem cells and their microenvironment. Using this approach, we have previously shown that restricted cell adhesion promotes terminal differentiation of human epidermal stem cells via activation of serum response factor...

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Detalles Bibliográficos
Autores principales: Connelly, John T., Mishra, Ajay, Gautrot, Julien E., Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206954/
https://www.ncbi.nlm.nih.gov/pubmed/22073300
http://dx.doi.org/10.1371/journal.pone.0027259