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Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats

BACKGROUND: Alpha 2 (α(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate the effects of dexmedetomidine and guanfacine (α(2)-adrenoceptor agonists) on...

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Detalles Bibliográficos
Autores principales:	Gursoy, Sinan, Ozdemir, Ercan, Bagcivan, Ihsan, Altun, Ahmet, Durmus, Nedim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207298/ https://www.ncbi.nlm.nih.gov/pubmed/21919812 http://dx.doi.org/10.3109/03009734.2011.597889

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