Spectroscopic-speckle variance OCT for microvasculature detection and analysis

We propose and studied optical coherence tomography (OCT) combining spectroscopic (SOCT) and speckle variance (svOCT) functions to effectively detect locations of microvasculatures and assess blood oxygen saturation level. Chorioallantoic membrane of a chick embryo was imaged in vivo to perform the...

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Detalles Bibliográficos
Autores principales: Liu, Xuan, Zhang, Kang, Huang, Yong, Kang, Jin U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Optical Coherence Tomography
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207370/
https://www.ncbi.nlm.nih.gov/pubmed/22076262
http://dx.doi.org/10.1364/BOE.2.002995
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author Liu, Xuan
Zhang, Kang
Huang, Yong
Kang, Jin U.
author_facet Liu, Xuan
Zhang, Kang
Huang, Yong
Kang, Jin U.
author_sort Liu, Xuan
collection PubMed
description We propose and studied optical coherence tomography (OCT) combining spectroscopic (SOCT) and speckle variance (svOCT) functions to effectively detect locations of microvasculatures and assess blood oxygen saturation level. Chorioallantoic membrane of a chick embryo was imaged in vivo to perform the analysis of the system. We also studied the effect of speckle in spectral domain using experimental data and performed time-averaging to reduce speckle noise locally. We combined SOCT and svOCT images using hue, saturation and value (HSV) color map to show the localized spectroscopic property of blood. Results show distinct spectroscopic properties between arterial blood and capillary blood.
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spelling pubmed-32073702011-11-10 Spectroscopic-speckle variance OCT for microvasculature detection and analysis Liu, Xuan Zhang, Kang Huang, Yong Kang, Jin U. Biomed Opt Express Optical Coherence Tomography We propose and studied optical coherence tomography (OCT) combining spectroscopic (SOCT) and speckle variance (svOCT) functions to effectively detect locations of microvasculatures and assess blood oxygen saturation level. Chorioallantoic membrane of a chick embryo was imaged in vivo to perform the analysis of the system. We also studied the effect of speckle in spectral domain using experimental data and performed time-averaging to reduce speckle noise locally. We combined SOCT and svOCT images using hue, saturation and value (HSV) color map to show the localized spectroscopic property of blood. Results show distinct spectroscopic properties between arterial blood and capillary blood. Optical Society of America 2011-10-04 /pmc/articles/PMC3207370/ /pubmed/22076262 http://dx.doi.org/10.1364/BOE.2.002995 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Optical Coherence Tomography
Liu, Xuan
Zhang, Kang
Huang, Yong
Kang, Jin U.
Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title_full Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title_fullStr Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title_full_unstemmed Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title_short Spectroscopic-speckle variance OCT for microvasculature detection and analysis
title_sort spectroscopic-speckle variance oct for microvasculature detection and analysis
topic Optical Coherence Tomography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207370/
https://www.ncbi.nlm.nih.gov/pubmed/22076262
http://dx.doi.org/10.1364/BOE.2.002995
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AT huangyong spectroscopicspecklevarianceoctformicrovasculaturedetectionandanalysis
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