Hedgehog signalling promotes germ cell survival in the rat testis

Hedgehog (Hh) signalling has a crucial role in testis development. Sertoli cell-derived desert hedgehog (DHH) guides the formation of testis cords and differentiation of foetal-type Leydig cells. Dhh mutant mice are infertile due to a block in germ cell differentiation, hypogonadism and hypoandrogen...

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Detalles Bibliográficos
Autores principales: Mäkelä, Juho-Antti, Saario, Vuokko, Bourguiba-Hachemi, Sonia, Nurmio, Mirja, Jahnukainen, Kirsi, Parvinen, Martti, Toppari, Jorma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207727/
https://www.ncbi.nlm.nih.gov/pubmed/21893610
http://dx.doi.org/10.1530/REP-11-0110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207727/
https://www.ncbi.nlm.nih.gov/pubmed/21893610
http://dx.doi.org/10.1530/REP-11-0110

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