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Hedgehog signalling promotes germ cell survival in the rat testis

Hedgehog (Hh) signalling has a crucial role in testis development. Sertoli cell-derived desert hedgehog (DHH) guides the formation of testis cords and differentiation of foetal-type Leydig cells. Dhh mutant mice are infertile due to a block in germ cell differentiation, hypogonadism and hypoandrogen...

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Detalles Bibliográficos
Autores principales:	Mäkelä, Juho-Antti, Saario, Vuokko, Bourguiba-Hachemi, Sonia, Nurmio, Mirja, Jahnukainen, Kirsi, Parvinen, Martti, Toppari, Jorma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207727/ https://www.ncbi.nlm.nih.gov/pubmed/21893610 http://dx.doi.org/10.1530/REP-11-0110

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