Cargando…
Drosophila Duplication Hotspots Are Associated with Late-Replicating Regions of the Genome
Duplications play a significant role in both extremes of the phenotypic spectrum of newly arising mutations: they can have severe deleterious effects (e.g. duplications underlie a variety of diseases) but can also be highly advantageous. The phenotypic potential of newly arisen duplications has stim...
Autores principales: | Cardoso-Moreira, Margarida, Emerson, J. J., Clark, Andrew G., Long, Manyuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207856/ https://www.ncbi.nlm.nih.gov/pubmed/22072977 http://dx.doi.org/10.1371/journal.pgen.1002340 |
Ejemplares similares
-
Evidence for the fixation of gene duplications by positive selection in Drosophila
por: Cardoso-Moreira, Margarida, et al.
Publicado: (2016) -
Deficiency of X-Linked Inverted Duplicates with Male-Biased Expression and the Underlying Evolutionary Mechanisms in the Drosophila Genome
por: Chen, Zhen-Xia, et al.
Publicado: (2011) -
Mutation spectrum of Drosophila CNVs revealed by breakpoint sequencing
por: Cardoso-Moreira, Margarida, et al.
Publicado: (2012) -
Late Replication Domains Are Evolutionary Conserved in the Drosophila Genome
por: Andreyenkova, Natalya G., et al.
Publicado: (2013) -
LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans
por: Tan, Shengjun, et al.
Publicado: (2016)