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Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control
BACKGROUND: The effects and effectiveness of the chaperone pair GroELS on the yield and quality of recombinant polypeptides produced in Escherichia coli are matter of controversy, as the reported activities of this complex are not always consistent and eventually indicate undesired side effects. The...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207889/ https://www.ncbi.nlm.nih.gov/pubmed/21992454 http://dx.doi.org/10.1186/1475-2859-10-79 |