SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic hypertrophic state. The restricted and reciprocal expression of the collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature cho...

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Detalles Bibliográficos
Autores principales: Leung, Victor Y. L., Gao, Bo, Leung, Keith K. H., Melhado, Ian G., Wynn, Sarah L., Au, Tiffany Y. K., Dung, Nelson W. F., Lau, James Y. B., Mak, Angel C. Y., Chan, Danny, Cheah, Kathryn S. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207907/
https://www.ncbi.nlm.nih.gov/pubmed/22072985
http://dx.doi.org/10.1371/journal.pgen.1002356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207907/
https://www.ncbi.nlm.nih.gov/pubmed/22072985
http://dx.doi.org/10.1371/journal.pgen.1002356

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