Cargando…

Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis

RNA sequencing provides a new perspective on the genome of Mycobacterium tuberculosis by revealing an extensive presence of non-coding RNA, including long 5’ and 3’ untranslated regions, antisense transcripts, and intergenic small RNA (sRNA) molecules. More than a quarter of all sequence reads mappi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arnvig, Kristine B., Comas, Iñaki, Thomson, Nicholas R., Houghton, Joanna, Boshoff, Helena I., Croucher, Nicholas J., Rose, Graham, Perkins, Timothy T., Parkhill, Julian, Dougan, Gordon, Young, Douglas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207917/ https://www.ncbi.nlm.nih.gov/pubmed/22072964 http://dx.doi.org/10.1371/journal.ppat.1002342

Ejemplares similares

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
por: Cortes, Teresa, et al.
Publicado: (2014)

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
por: Cortes, Teresa, et al.
Publicado: (2013)

Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis
por: Arnvig, Kristine, et al.
Publicado: (2012)

Identification of small RNAs in Mycobacterium tuberculosis
por: Arnvig, Kristine B, et al.
Publicado: (2009)

The Mycobacterium tuberculosis sRNA F6 Modifies Expression of Essential Chaperonins, GroEL2 and GroES
por: Houghton, Joanna, et al.
Publicado: (2021)

A Small RNA Encoded in the Rv2660c Locus of Mycobacterium tuberculosis Is Induced during Starvation and Infection
por: Houghton, Joanna, et al.
Publicado: (2013)

Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis
por: Moores, Alexandra, et al.
Publicado: (2017)

A simple method for directional transcriptome sequencing using Illumina technology
por: Croucher, Nicholas J., et al.
Publicado: (2009)

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex
por: Chiner-Oms, Álvaro, et al.
Publicado: (2019)

Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis
por: Schwenk, Stefan, et al.
Publicado: (2018)

A Strand-Specific RNA–Seq Analysis of the Transcriptome of the Typhoid Bacillus Salmonella Typhi
por: Perkins, Timothy T., et al.
Publicado: (2009)

Genomic Epidemiology of Vibrio cholerae O1 Associated with Floods, Pakistan, 2010
por: Shah, Muhammad Ali, et al.
Publicado: (2014)

Draft Genome Sequence of Mycobacterium brumae ATCC 51384
por: D'Auria, Giuseppe, et al.
Publicado: (2016)

Comment on: Characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array
por: Köser, Claudio U., et al.
Publicado: (2014)

Identification, variation and transcription of pneumococcal repeat sequences
por: Croucher, Nicholas J, et al.
Publicado: (2011)

Mapping of Genotype–Phenotype Diversity among Clinical Isolates of Mycobacterium tuberculosis by Sequence-Based Transcriptional Profiling
por: Rose, Graham, et al.
Publicado: (2013)

Characterization of the MurT/GatD complex in Mycobacterium tuberculosis towards validating a novel anti-tubercular drug target
por: Maitra, Arundhati, et al.
Publicado: (2021)

Global Analysis of the Regulon of the Transcriptional Repressor LexA, a Key Component of SOS Response in Mycobacterium tuberculosis
por: Smollett, Katherine L., et al.
Publicado: (2012)

Phylogenetic analysis of vitamin B12-related metabolism in Mycobacterium tuberculosis
por: Young, Douglas B., et al.
Publicado: (2015)

A new spanner in the works of bacterial transcription
por: Arnvig, Kristine B, et al.
Publicado: (2014)

Editorial: Drug-resistant Mycobacterium tuberculosis
por: Boshoff, Helena I. M., et al.
Publicado: (2023)

A High-Resolution View of Genome-Wide Pneumococcal Transformation
por: Croucher, Nicholas J., et al.
Publicado: (2012)

Mycobacterium tuberculosis cAMP Receptor Protein (Rv3676) Differs from the Escherichia coli Paradigm in Its cAMP Binding and DNA Binding Properties and Transcription Activation Properties
por: Stapleton, Melanie, et al.
Publicado: (2010)

Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee
por: Coscolla, Mireia, et al.
Publicado: (2013)

Genetic flux over time in the Salmonella lineage
por: Vernikos, Georgios S, et al.
Publicado: (2007)

Draft Genome Sequence of 24570, the Type Strain of Shigella flexneri
por: Baker, Kate S., et al.
Publicado: (2015)

Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies
por: Comas, Iñaki, et al.
Publicado: (2009)

Studying bacterial transcriptomes using RNA-seq
por: Croucher, Nicholas J, et al.
Publicado: (2010)

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis
por: Watanabe, Shinya, et al.
Publicado: (2011)

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages
por: Portevin, Damien, et al.
Publicado: (2011)

Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity
por: Chiner-Oms, Álvaro, et al.
Publicado: (2018)

High-Resolution Single Nucleotide Polymorphism Analysis Distinguishes Recrudescence and Reinfection in Recurrent Invasive Nontyphoidal Salmonella Typhimurium Disease
por: Okoro, Chinyere K., et al.
Publicado: (2012)

A Study on the Geophylogeny of Clinical and Environmental Vibrio cholerae in Kenya
por: Kiiru, John, et al.
Publicado: (2013)

Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection
por: Chiner-Oms, Álvaro, et al.
Publicado: (2022)

Uncovering the Mast Cell Response to Mycobacterium tuberculosis
por: Torres-Atencio, Ivonne, et al.
Publicado: (2022)

Lack of methoxy-mycolates characterizes the geographically restricted lineage 7 of Mycobacterium tuberculosis complex
por: Hailu, Elena, et al.
Publicado: (2023)

Prospective Surveillance and Rapid Whole-Genome Sequencing Detects Two Unsuspected Outbreaks of Carbapenemase-Producing Klebsiella pneumoniae in a UK Teaching Hospital
por: Torok, Estee, et al.
Publicado: (2017)

SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data
por: Gabbassov, Einar, et al.
Publicado: (2021)

Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach
por: Everett, Dean B., et al.
Publicado: (2012)

Relative Abundance of Transcripts ( RATs): Identifying differential isoform abundance from RNA-seq
por: Froussios, Kimon, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oavvi9qdsljdu4efqsuoehlj16