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Chemoresistance of glioblastoma cancer stem cells - much more complex than expected

Glioblastomas (GBM) are a paradigm for the investigation of cancer stem cells (CSC) in solid malignancies. The susceptibility of GBM CSC to standard chemotherapeutic drugs is controversial as the existing literature presents conflicting experimental data. Here, we summarize the experimental evidence...

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Detalles Bibliográficos
Autores principales: Beier, Dagmar, Schulz, Joerg B, Beier, Christoph P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207925/
https://www.ncbi.nlm.nih.gov/pubmed/21988793
http://dx.doi.org/10.1186/1476-4598-10-128