Interspecies Translation of Disease Networks Increases Robustness and Predictive Accuracy

Gene regulatory networks give important insights into the mechanisms underlying physiology and pathophysiology. The derivation of gene regulatory networks from high-throughput expression data via machine learning strategies is problematic as the reliability of these models is often compromised by li...

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Detalles Bibliográficos
Autores principales: Anvar, Seyed Yahya, Tucker, Allan, Vinciotti, Veronica, Venema, Andrea, van Ommen, Gert-Jan B., van der Maarel, Silvere M., Raz, Vered, ‘t Hoen, Peter A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207951/
https://www.ncbi.nlm.nih.gov/pubmed/22072955
http://dx.doi.org/10.1371/journal.pcbi.1002258

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