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Systematic analysis of mitochondrial genes associated with hearing loss in the Japanese population: dHPLC reveals a new candidate mutation

BACKGROUND: Variants of mitochondrial DNA (mtDNA) have been evaluated for their association with hearing loss. Although ethnic background affects the spectrum of mtDNA variants, systematic mutational analysis of mtDNA in Japanese patients with hearing loss has not been reported. METHODS: Using denat...

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Detalles Bibliográficos
Autores principales: Mutai, Hideki, Kouike, Hiroko, Teruya, Eiko, Takahashi-Kodomari, Ikuko, Kakishima, Hiroki, Taiji, Hidenobu, Usami, Shin-ichi, Okuyama, Torayuki, Matsunaga, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207971/
https://www.ncbi.nlm.nih.gov/pubmed/21989059
http://dx.doi.org/10.1186/1471-2350-12-135