Cargando…
Microtubules induce self-organization of polarized PAR domains in C. elegans zygotes
A hallmark of polarized cells is the segregation of the PAR polarity regulators into asymmetric domains at the cell cortex(1, 2). Antagonistic interactions involving two conserved kinases, atypical protein kinase C (aPKC) and PAR-1, have been implicated in polarity maintenance(1, 2), but the mechani...
Autores principales: | Motegi, Fumio, Zonies, Seth, Hao, Yingsong, Cuenca, Adrian A., Griffin, Erik, Seydoux, Geraldine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208083/ https://www.ncbi.nlm.nih.gov/pubmed/21983565 http://dx.doi.org/10.1038/ncb2354 |
Ejemplares similares
-
Revisiting the role of microtubules in C. elegans polarity
por: Motegi, Fumio, et al.
Publicado: (2007) -
The PAR network: redundancy and robustness in a symmetry-breaking system
por: Motegi, Fumio, et al.
Publicado: (2013) -
Mechanochemical Control of Symmetry Breaking in the Caenorhabditis elegans Zygote
por: Gan, Wan Jun, et al.
Publicado: (2021) -
PAR proteins regulate maintenance-phase myosin dynamics during Caenorhabditis elegans zygote polarization
por: Small, Lawrence E., et al.
Publicado: (2017) -
Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms
por: Folkmann, Andrew W., et al.
Publicado: (2019)