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Salvage surgery for a giant melanoma on the back

We report a case of a giant melanoma on the back with a very extreme Breslow thickness. On physical examination a large odorous and ulcerating tumour was seen adjacent to two large crusted lesions, probably in transit metastases. In the right and left axilla enlarged lymph nodes were palpated. The p...

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Autores principales: Kruijff, Schelto, Vink, Robert, Klaase, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208415/
https://www.ncbi.nlm.nih.gov/pubmed/22066035
http://dx.doi.org/10.4081/rt.2011.e28
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author Kruijff, Schelto
Vink, Robert
Klaase, Joost
author_facet Kruijff, Schelto
Vink, Robert
Klaase, Joost
author_sort Kruijff, Schelto
collection PubMed
description We report a case of a giant melanoma on the back with a very extreme Breslow thickness. On physical examination a large odorous and ulcerating tumour was seen adjacent to two large crusted lesions, probably in transit metastases. In the right and left axilla enlarged lymph nodes were palpated. The patient underwent salvage surgery consisting of a complete wide excision of the tumors on the back as well as axillary lymph node dissection on both sides. Histopathology showed a malignant melanoma with a Breslow thickness of 48 mm. Four of fifteen nodes in the right axilla and one of nine nodes in the left axilla, were positive for metastatic disease. Also various in transit and subcutaneous metastases were found in the wide excision specimen. The interest of our observation relies in the rarity of a melanoma with such an extreme Breslow thickness and the difficulty in performing adequate palliative therapy that offers quality of life by means of tumor control.
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spelling pubmed-32084152011-11-07 Salvage surgery for a giant melanoma on the back Kruijff, Schelto Vink, Robert Klaase, Joost Rare Tumors Case Report We report a case of a giant melanoma on the back with a very extreme Breslow thickness. On physical examination a large odorous and ulcerating tumour was seen adjacent to two large crusted lesions, probably in transit metastases. In the right and left axilla enlarged lymph nodes were palpated. The patient underwent salvage surgery consisting of a complete wide excision of the tumors on the back as well as axillary lymph node dissection on both sides. Histopathology showed a malignant melanoma with a Breslow thickness of 48 mm. Four of fifteen nodes in the right axilla and one of nine nodes in the left axilla, were positive for metastatic disease. Also various in transit and subcutaneous metastases were found in the wide excision specimen. The interest of our observation relies in the rarity of a melanoma with such an extreme Breslow thickness and the difficulty in performing adequate palliative therapy that offers quality of life by means of tumor control. PAGEPress Publications 2011-07-11 /pmc/articles/PMC3208415/ /pubmed/22066035 http://dx.doi.org/10.4081/rt.2011.e28 Text en ©Copyright S. Kruijff et al., 2011 This work is licensed under a Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0). Licensee PAGEPress, Italy
spellingShingle Case Report
Kruijff, Schelto
Vink, Robert
Klaase, Joost
Salvage surgery for a giant melanoma on the back
title Salvage surgery for a giant melanoma on the back
title_full Salvage surgery for a giant melanoma on the back
title_fullStr Salvage surgery for a giant melanoma on the back
title_full_unstemmed Salvage surgery for a giant melanoma on the back
title_short Salvage surgery for a giant melanoma on the back
title_sort salvage surgery for a giant melanoma on the back
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208415/
https://www.ncbi.nlm.nih.gov/pubmed/22066035
http://dx.doi.org/10.4081/rt.2011.e28
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