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Src homology domain-containing phosphatase 2 suppresses cellular senescence in glioblastoma

BACKGROUND: Epidermal growth factor receptor (EGFR) signalling is frequently altered during glioblastoma de novo pathogenesis. An important downstream modulator of this signal cascade is SHP2 (Src homology domain-containing phosphatase 2). METHODS: We examined the The Cancer Genome Atlas (TCGA) data...

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Detalles Bibliográficos
Autores principales:	Sturla, L-M, Zinn, P O, Ng, K, Nitta, M, Kozono, D, Chen, C C, Kasper, E M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208488/ https://www.ncbi.nlm.nih.gov/pubmed/21934682 http://dx.doi.org/10.1038/bjc.2011.345

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