Cargando…

Interleukin-1 as an Injury Signal Mobilizes Retinyl Esters in Hepatic Stellate Cells through Down Regulation of Lecithin Retinol Acyltransferase

Retinoids are mostly stored as retinyl esters in hepatic stellate cells (HSCs) through esterification of retinol and fatty acid, catalyzed by lecithin-retinol acyltransferase (LRAT). This study is designated to address how retinyl esters are mobilized in liver injury for tissue repair and wound heal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kida, Yujiro, Xia, Zanxian, Zheng, Sujun, Mordwinkin, Nicholas M., Louie, Stan G., Zheng, Song Guo, Feng, Min, Shi, Hongbo, Duan, Zhongping, Han, Yuan-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208544/ https://www.ncbi.nlm.nih.gov/pubmed/22073179 http://dx.doi.org/10.1371/journal.pone.0026644

Ejemplares similares

Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation
por: Wagner, Carina, et al.
Publicado: (2020)

Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores
por: Grumet, Lukas, et al.
Publicado: (2016)

Retinol Metabolism in the Mollusk Osilinus lineatus Indicates an Ancient Origin for Retinyl Ester Storage Capacity
por: Gesto, Manuel, et al.
Publicado: (2012)

Diacylglycerol O-Acyltransferase Type-1 Synthesizes Retinyl Esters in the Retina and Retinal Pigment Epithelium
por: Kaylor, Joanna J., et al.
Publicado: (2015)

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells
por: Wagner, Carina, et al.
Publicado: (2022)

Retinol and Retinyl Palmitate in Foetal Lung Mice: Sexual Dimorphism
por: Carvalho, Olga, et al.
Publicado: (2013)

Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation
por: Testerink, Nicole, et al.
Publicado: (2012)

Retinyl ester hydrolases and their roles in vitamin A homeostasis()
por: Schreiber, Renate, et al.
Publicado: (2012)

High-Density Lipoprotein, Lecithin: Cholesterol Acyltransferase, and Atherosclerosis
por: Ossoli, Alice, et al.
Publicado: (2016)

Retinyl esters form lipid droplets independently of triacylglycerol and seipin
por: Molenaar, Martijn R., et al.
Publicado: (2021)

Corneal thickness in the case of familial lecithin-cholesterol acyltransferase deficiency
por: Kinoshita, Shinsuke, et al.
Publicado: (2021)

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
por: Grumet, Lukas, et al.
Publicado: (2016)

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
por: Pirazzi, Carlo, et al.
Publicado: (2014)

Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase
por: Glukhova, Alisa, et al.
Publicado: (2015)

Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria
por: Althaf, Mohammed Mahdi, et al.
Publicado: (2015)

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation
por: Pajed, Laura, et al.
Publicado: (2019)

A simple and robust quantitative analysis of retinol and retinyl palmitate using a liquid chromatographic isocratic method
por: Yokota, Satoshi, et al.
Publicado: (2017)

Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye
por: Imanishi, Yoshikazu, et al.
Publicado: (2004)

Alcohol acyltransferases for the biosynthesis of esters
por: Liu, Gaofei, et al.
Publicado: (2023)

Lecithin: Cholesterol Acyltransferase and Na(+)-K(+)-ATPase Activity in Patients with Breast Cancer
por: Özmen, Hilal Kiziltunç, et al.
Publicado: (2013)

Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles
por: Manthei, Kelly A., et al.
Publicado: (2020)

Safety and Proof-of-Concept Study of Oral QLT091001 in Retinitis Pigmentosa Due to Inherited Deficiencies of Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT)
por: Scholl, Hendrik P. N., et al.
Publicado: (2015)

Development of two reference materials for all trans-retinol, retinyl palmitate, α- and γ-tocopherol in milk powder and infant formula
por: Shehata, Adel B., et al.
Publicado: (2014)

Plasma Lecithin-Cholesterol Acyltransferase Activity in Pregnant Women Enrolled in the iLiNS-DYAD Trial in Ghana
por: Hong, Brian, et al.
Publicado: (2022)

Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides
por: Casteleijn, Marco G., et al.
Publicado: (2018)

Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol
por: Manthei, Kelly A, et al.
Publicado: (2018)

Low Plasma Lecithin: Cholesterol Acyltransferase (LCAT) Concentration Predicts Chronic Kidney Disease
por: Baragetti, Andrea, et al.
Publicado: (2020)

A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency
por: Vitali, Cecilia, et al.
Publicado: (2022)

Two novel variants in the lecithin:cholesterol acyltransferase gene resulted in classic LCAT deficiency
por: Fistrek Prlic, Margareta, et al.
Publicado: (2022)

Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
por: Gunawardane, Ruwanthi N., et al.
Publicado: (2016)

Two novel mutations of lecithin:cholesterol acyltransferase (LCAT) gene and the influence of APOE genotypes on clinical manifestations
por: Katayama, Akihiro, et al.
Publicado: (2011)

Beta2-adrenergic activity modulates vascular tone regulation in lecithin:cholesterol acyltransferase knockout mice
por: Manzini, S., et al.
Publicado: (2015)

Identification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia
por: Tobar, Hugo E., et al.
Publicado: (2019)

Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings
por: Norum, Kaare R., et al.
Publicado: (2020)

Vitamin A Absorption Efficiency Determined by Compartmental Analysis of Postprandial Plasma Retinyl Ester Kinetics in Theoretical Humans
por: Green, Michael H, et al.
Publicado: (2020)

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle
por: Hara, Miwa, et al.
Publicado: (2023)

Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia
por: Conca, Paola, et al.
Publicado: (2012)

Familial lecithin-cholesterol acyltransferase deficiency: If so rare, why so frequent in the state of Piauí, northeastern Brazil?
por: de Serpa Brandão, Rafael Melo Santos, et al.
Publicado: (2022)

Influence of lecithin cholesterol acyltransferase alteration during different pathophysiologic conditions: A 45 years bibliometrics analysis
por: Gao, Hongliang, et al.
Publicado: (2022)

Corrigendum: Influence of lecithin cholesterol acyltransferase alteration during different pathophysiologic conditions: A 45 years bibliometrics analysis
por: Gao, Hongliang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_inpqou592c90f3qo6cltipse02