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Acute Overactive Endocannabinoid Signaling Induces Glucose Intolerance, Hepatic Steatosis, and Novel Cannabinoid Receptor 1 Responsive Genes
Endocannabinoids regulate energy balance and lipid metabolism by stimulating the cannabinoid receptor type 1 (CB1). Genetic deletion and pharmacological antagonism have shown that CB1 signaling is necessary for the development of obesity and related metabolic disturbances. However, the sufficiency o...
Autores principales: | Ruby, Maxwell A., Nomura, Daniel K., Hudak, Carolyn S. S., Barber, Anne, Casida, John E., Krauss, Ronald M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208546/ https://www.ncbi.nlm.nih.gov/pubmed/22073164 http://dx.doi.org/10.1371/journal.pone.0026415 |
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