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Moderate Antiproteinuric Effect of Add-On Aldosterone Blockade with Eplerenone in Non-Diabetic Chronic Kidney Disease. A Randomized Cross-Over Study

BACKGROUND: Reduction of proteinuria and blood pressure (BP) with blockers of the renin-angiotensin system (RAS) impairs the progression of chronic kidney disease (CKD). The aldosterone antagonist spironolactone has an antiproteinuric effect, but its use is limited by side effects. The present study...

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Detalles Bibliográficos
Autores principales: Boesby, Lene, Elung-Jensen, Thomas, Klausen, Tobias Wirenfeldt, Strandgaard, Svend, Kamper, Anne-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208556/
https://www.ncbi.nlm.nih.gov/pubmed/22073219
http://dx.doi.org/10.1371/journal.pone.0026904