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Context Mediates Antimicrobial Efficacy of Kinocidin Congener Peptide RP-1
Structure-mechanism relationships are key determinants of host defense peptide efficacy. These relationships are influenced by anatomic, physiologic and microbiologic contexts. Structure-mechanism correlates were assessed for the synthetic peptide RP-1, modeled on microbicidal domains of platelet ki...
Autores principales: | Yount, Nannette Y., Cohen, Samuel E., Kupferwasser, Deborah, Waring, Alan J., Ruchala, Piotr, Sharma, Shantanu, Wasserman, Karlman, Jung, Chun-Ling, Yeaman, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208557/ https://www.ncbi.nlm.nih.gov/pubmed/22073187 http://dx.doi.org/10.1371/journal.pone.0026727 |
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