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Regulation of IL-2 gene expression by Siva and FOXP3 in human T cells

BACKGROUND: Severe autoinflammatory diseases are associated with mutations in the Foxp3 locus in both mice and humans. Foxp3 is required for the development, function, and maintenance of regulatory T cells (T(regs)), a subset of CD4 cells that suppress T cell activation and inflammatory processes. S...

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Detalles Bibliográficos
Autores principales: Hench, Virginia K, Su, Lishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208582/
https://www.ncbi.nlm.nih.gov/pubmed/21955384
http://dx.doi.org/10.1186/1471-2172-12-54