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Age-Associated Disruption of Molecular Clock Expression in Skeletal Muscle of the Spontaneously Hypertensive Rat

It is well known that spontaneously hypertensive rats (SHR) develop muscle pathologies with hypertension and heart failure, though the mechanism remains poorly understood. Woon et al. (2007) linked the circadian clock gene Bmal1 to hypertension and metabolic dysfunction in the SHR. Building on these...

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Detalles Bibliográficos
Autores principales:	Miyazaki, Mitsunori, Schroder, Elizabeth, Edelmann, Stephanie E., Hughes, Michael E., Kornacker, Karl, Balke, C. William, Esser, Karyn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208587/ https://www.ncbi.nlm.nih.gov/pubmed/22076133 http://dx.doi.org/10.1371/journal.pone.0027168

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