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Inner ear dysfunction in caspase-3 deficient mice
BACKGROUND: Caspase-3 is one of the most downstream enzymes activated in the apoptotic pathway. In caspase-3 deficient mice, loss of cochlear hair cells and spiral ganglion cells coincide closely with hearing loss. In contrast with the auditory system, details of the vestibular phenotype have not be...
Autores principales: | Makishima, Tomoko, Hochman, Lara, Armstrong, Patrick, Rosenberger, Eric, Ridley, Ryan, Woo, Minna, Perachio, Adrian, Wood, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208590/ https://www.ncbi.nlm.nih.gov/pubmed/21988729 http://dx.doi.org/10.1186/1471-2202-12-102 |
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