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Inner ear dysfunction in caspase-3 deficient mice

BACKGROUND: Caspase-3 is one of the most downstream enzymes activated in the apoptotic pathway. In caspase-3 deficient mice, loss of cochlear hair cells and spiral ganglion cells coincide closely with hearing loss. In contrast with the auditory system, details of the vestibular phenotype have not be...

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Detalles Bibliográficos
Autores principales: Makishima, Tomoko, Hochman, Lara, Armstrong, Patrick, Rosenberger, Eric, Ridley, Ryan, Woo, Minna, Perachio, Adrian, Wood, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208590/
https://www.ncbi.nlm.nih.gov/pubmed/21988729
http://dx.doi.org/10.1186/1471-2202-12-102

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