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Indirect Detection of an Epitope-Specific Response to HIV-1 gp120 Immunization in Human Subjects
A specific response of human serum neutralizing antibodies (nAb) to a conformational epitope as a result of vaccination of human subjects with the surface envelope glycoprotein (gp120) of HIV-1 has not previously been documented. Here, we used computational analysis to assess the epitope-specific re...
Autores principales: | Shmelkov, Evgeny, Nadas, Arthur, Swetnam, James, Zolla-Pazner, Susan, Cardozo, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208624/ https://www.ncbi.nlm.nih.gov/pubmed/22076145 http://dx.doi.org/10.1371/journal.pone.0027279 |
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