Upregulation of Cardiomyocyte Ribonucleotide Reductase Increases Intracellular 2 deoxy-ATP, Contractility, and Relaxation

We have previously demonstrated that substitution of ATP with 2 deoxy-ATP (dATP) increased the magnitude and rate of force production at all levels of Ca(2+)-mediated activation in demembranated cardiac muscle. In the current study we hypothesized that cellular [dATP] could be increased by viral-med...

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Detalles Bibliográficos
Autores principales: Korte, F. Steven, Dai, Jin, Buckley, Kate, Feest, Erik R., Adamek, Nancy, Geeves, Michael A., Murry, Charles E., Regnier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208740/
https://www.ncbi.nlm.nih.gov/pubmed/21925507
http://dx.doi.org/10.1016/j.yjmcc.2011.08.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208740/
https://www.ncbi.nlm.nih.gov/pubmed/21925507
http://dx.doi.org/10.1016/j.yjmcc.2011.08.026

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